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As part of the QBRI External Webinar Series, Dr. Gaia Novarino, a professor at the Institute of Science and Technology Austria, will present her research on the genetic foundations of autism spectrum disorder (ASD).
The study investigates how different genetic mutations influence molecular and cellular changes in the brain. The cohort includes 11 mouse lines and span chromatin remodelers, ubiquitin-related genes, metabolically relevant genes, and synaptic proteins. Advanced techniques, including single-nucleus RNA and ATAC sequencing across brain regions, developmental stages, and sexes, are employed to analyze patterns of convergence and divergence across ASD models, developmental stages, and sex-specific differences.
This webinar will discuss these findings and explain their impact on ASD research.
