Genomics in Clinical Practice

College of Health and Life Sciences

Discussions will be in English.

QCHP

This activity is an Accredited Group Learning Activity (Category 1) as defined by the Qatar Council for Healthcare Practitioners- Accreditation Department (QCHP-AD) and is approved for a maximum of 5.75 hours.

Physicians, trainee physicians, and medical students are invited to attend the ‘Genomics in Clinical Practice’ seminar, which will focus on genomics and genome sequencing technologies.

This Symposium aims to address the following educational objectives:

Discover the science behind genomics, DNA sequencing, and the implications for patient care
Increase awareness among medical practitioners of the available technologies, facilities, and resources in genomics in Qatar
Ensure that physicians and future members of health care teams have the skills to integrate genomic information in practice
Explore how the fundamentals of genomics are being used for understanding the pathophysiology of the disease.

Overall Learning Objectives:
At the end of the symposium, participants will be able to:

Define the basic science behind genomics, DNA sequencing, and the implications for patient care.
Identify the available technologies, facilities and resources in Genomics in Doha.
Determine the use of genomic information and genetic testing in clinical practice.
Recognize how the genomics are being used for understanding the pathophysiology of complex diseases such as diabetes and cardiovascular diseases.

Program Overview

Time	Speakers and Talks	Session Learning Outcomes
Time: 8:30 am – 9:00 am	Registration/Coffee
Time: 9:00 am – 9:10 am	Welcome and Introduction Dr. Edward Stuenkel Dean, College of Health and Life Sciences
Time: 9:10 am – 12:30 am	Speakers and Talks: GENOMICS: TECHNOLOGIES AND PLATFORMS Moderator (Dr. Nady El Hajj) Assistant Professor, College of Health and Life Sciences, HBKU	Session Learning Outcomes: Learning Outcomes
Time: 9:20 am –10:00 am	Speakers and Talks: Dr. Ihab Younis Assistant Teaching Professor Carnegie Mellon University in Qatar Talk Title Introducing basic genomics	Session Learning Outcomes: Explain the chromatin and gene structure, basics of genomics and aspects of gene regulation Illustrate the concepts of polymorphisms and DNA sequence variations (single nucleotide variants, copy number variations) State the concepts of Genome-Wide Association Studies and Precision medicine
Time: 10:00 – 10:15	Discussion - Q & A
Time: 10:15 am – 10:45 am	Speakers and Talks: Dr. Chidambaram Manickam Staff Scientist, Integrated Genomics Services Sidra Medicine Talk Title Genomic technologies in Qatar	Session Learning Outcomes: Describe technologies of high throughput next-generation genomic sequencing Outline the high throughput sequencing technologies for a wide range of biomedical and clinical applications Highlight the activities and services provided by the Human Genotyping Facility at Sidra Medicine
Time: 10:45 - 11:00	Discussion - Q & A
Time: 11:00 am – 11:40 am	Speakers and Talks: Dr. Tawfeg Ben-Omran Head, Clinical and Metabolic Genetics, Hamad Medical Corporation Associate Professor, Weill Cornell Medical College Talk Title Exome sequencing in clinical practice	Session Learning Outcomes: Highlight the important role of genetic studies in the early detection and diagnosis of genetic disorders. Demonstrate the exchange of expertise and ideas between scientific and health organizations
Time: 11:40 - 12:00	Discussion - Q & A
Time: 12:00 pm – 1:30 pm	Lunch break
Time: 1:30 pm – 5:00 pm	Speakers and Talks: CLINICAL APPLICATIONS OF GENOMICS Moderator: Dr. Omar Albagha Principal Investigator, Qatar Biomedical Research Institute, HBKU
Time: 1:30 pm – 2:10 pm	Speakers and Talks: Dr. Said Ismail Manager, Qatar Genome Programme Talk Title What is Qatar Genome Programme?”	Session Learning Outcomes: Deliver an overview of Qatar Genome Programme’s vision and structure with special emphasis on the bioinformatics work being carried out in Qatar Evaluate Qatar Genome Project plans to facilitate clinical implementation of genomics in clinical care settings.
Time: 2:10 – 2:25	Discussion - Q & A
Time: 2:25 pm – 3:05 pm	Speakers and Talks: Dr. Donald Love Head, Division of Pathology Genetics Sidra Medicine Talk Title Diagnostic Genetics: seeing through a glass, darkly	Session Learning Outcomes: Illustrate the role of whole exome sequencing in clinics Describe how genomic variants can be classified Discuss the patient awareness of the implications of whole exome sequencing. Indicate the closures in the event of finding a pathogenic variant.
Time: 3:05 pm - 03:20 pm	Discussion - Q & A
Time: 3:20 pm – 3:40 pm	Coffee Break
Time: 3:40 pm – 4:40 pm 1 CME point	Speakers and Talks: *Keynote lecture: Dr. André Uitterlinden* Professor, Department of Internal Medicine, Genetic Laboratory, Erasmus University, Rotterdam (Netherland) Talk Title Genomics for complex disorders	Session Learning Outcomes: Present an overview of the different types of ‘omics’ that are currently available Outline the many technological developments that have led to the genome-wide analysis at population levels (Translational Genomics) Discuss the genome-wide association studies of diseases with complex genetic traits, including diabetes mellitus, osteoporosis, and cardiovascular disease
Time: 4:40 pm – 4:55 pm	*Discussion - Q & A*
Time: 4:55 pm – 5:00 pm	Conclusion and remarks
Time: 5:00 pm – 5:30 pm	Networking reception

“The Scientific Planning Committee has reviewed all disclosed financial relationships of speakers, moderators, facilitators, and/or authors in advance of this CPD activity and has implemented procedures to manage any potential or real conflicts of interest.”