Dr. Lawrence Stanton
Director, Neurological Disorders Research Center Joint Professor
Dr. Lawrence Stanton
Director, Neurological Disorders Research Center Joint Professor
Educational Qualifications
PhD in Biochemistry
Post-doctoral fellowship
Entity
Qatar Biomedical Research Institute
College of Health and Life Sciences
Divison
Neurological Disorders Research Center
Biography
Dr. Lawrence Stanton joined QBRI in 2019 with more than 30 years of research experience in industry and academia. His research is focused on dissecting the molecular pathways that underly neurodevelopmental disorders, including autism. After earning a PhD in biochemistry at Stony Brook University (USA), he completed a post-doctoral fellowship in cancer biology at University of California San Francisco (USA) under the guidance of Nobel Laureate, Dr. Michael Bishop.
At QBRI the Stanton lab is generating induced pluripotent stem cells (iPSC) from patients with neurodevelopmental disorders. These patient-specific iPSC are converted into neural cell types and organoids, thus providing an opportunity to understand the molecular pathology of diseases such as autism and establishing a foundation for the development of diagnostics and therapeutics to treat patients with neurodevelopmental disorders.
PhD in Biochemistry
Stony Brook University (USA)
Post-doctoral fellowship
University of California San Francisco (USA)
- Molecular characterization of gene regulatory networks
- Disease modeling neurodevelopmental disorders
- Disease modeling diabetes
- Stem cell biology
- Genomics
Group Leader
Scios Inc, USA
1990 - 2000
Director Functional Genomics
Geron Corp, USA
2001 - 2002
Deputy Director
Genome Institute of Singapore
2002 - 2016
Executive Director
Humacyte Inc., USA
2017 - 2019
- Single cell transcriptomics identifies master regulators of neurodegeneration in SOD1 ALS iPSC-derived motor neurons. Stem Cell Reports. 2021; 16(12):3020-35.
- Cool SM*(Co-senior authors). A genomic biomarker that identifies human bone marrow-derived mesenchymal stem cells with high scalability. Stem Cells. 2020; 38(9):1124-1136.
- Rapid generation of purified human RPE from pluripotent stem cells using 2D cultures and lipoprotein uptake-based sorting. Stem Cell Res Ther. 2020; 11(1):47.
- Sheila M, Narayanan, G, Ma S, Tam WL, Chai J and Lawrence W Stanton Neurobiology of Disease 124, p1-13 (2019)
- Wang J, Jenjaroenpun P, Bhinge A, Angarica VE, Del Sol A, Nookaew I, Kuznetsov VA, and Lawrence W Stanton Genome Research 27(11), p1783-1794 (2017)
- Bhinge A, Namboori S, and Lawrence W. Stanton Stem Cell Reports 8(4), p856-69 (2017)
- Lin L, Goke, J, Cukuroglu E, Dranias MR, Van Dongen AMJ, and Lawrence W. Stanton Cell Reports 15(11), p2411-26 (2016)
- Bhinge A, Namboori S Angela Bithell, Soldati AC, Buckley NJ, Lawrence W. Stanton Stem Cells 34(1), p124-34 (2016)
- Bhinge A, Poschman J, Tian XF, Loh JH, Traczyk A, Prabhakar S, and Lawrence W. Stanton EMBO J 33(11), p1271-83 (2014)
- Ng SY, Bogu G, Soh BS, and Lawrence W. Stanton Molecular Cell 51(3), p349-59 (2013)
- 2011 President’s Science and Technology Award, Singapore
- 2012 Outstanding Mentorship Award
- 2014 UK-Southeast Asia Partnership Award
- 2014 International Visiting Professorship, Chinese Academy of Sciences
- 2016-17 President, Stem Cell Society of Singapore
- 2008-present Associate Editor, Stem Cells journal