Human pluripotent stem cells (hPSCs) that include induced pluripotent stem cells (iPSCs) and embryonic stem cells (ESCs) provide an excellent platform for studying human development, disease progression modeling, drug screens and cell-based therapies.
The main objective of the Stem Cells and Genome Engineering Core is to facilitate the development of basic and translational stem cell research by providing scientific advice, iPSCs derivation, directed differentiations and genome engineering services to researchers. The facility is fully equipped with standard and state-of-the-art cell culture, cell biology and molecular biology equipment.
The Stem Cells and Genome Engineering Core is currently working with QBRI’s Neurological disorders, Diabetes teams and with Harvard Stem Cell Institute for generation and engineering of iPSCs and their directed differentiation into cortical neurons, brain organoids as well as pancreatic beta cells.