Johan Ericsson | Hamad Bin Khalifa University

Dr. Johan Ericsson

Associate Professor

Phone

55 341 809

Office location

LAS Building, Room B138

Dr. Johan Ericsson

Associate Professor

Educational Qualifications

Postdoctoral Fellow

PhD

Entity

College of Health and Life Sciences

Biography

Dr. Ericsson attended both Uppsala and Stockholm University and obtained his PhD from Stockholm University in 1992. He then moved to the University of California-Los Angeles (UCLA), where he worked on the transcriptional regulation of cholesterol metabolism. 

Dr. Ericsson established his own independent research group in 1998 at the Ludwig Institute for Cancer Research, focusing on the post-translational regulation of a family of transcription factors critical for cholesterol and lipid metabolism, i.e. the SREBP family of proteins. In 2009, Dr. Ericsson became an SFI Stokes Professor at University College Dublin, where his group continued their work on the transcriptional and post-translational regulation of lipid metabolism. Dr. Ericsson has been an Associate Professor at HBKU since May 2019.

 

Postdoctoral Fellow

Departments of Biological Chemistry and Medicine, University of California, Los Angeles, USA.

1993 - 1995

PhD

Stockholm University, Department of Biochemistry.

1992

Associate Professor

Hamad Bin Khalifa University, College of Medical and Life Sciences.

2019

SFI Stokes Professor

UCD Conway Institute, School of Medicine and Medical Science, University College Dublin.

2009 - 2019

Associate Member & Group Leader

Gene Expression Laboratory, Ludwig Institute for Cancer Research, Uppsala, Sweden.

2004 - 2008

Research Fellow

Royal Swedish Academy of Sciences.

2002 - 2007

Assistant Member & Group Leader

Gene Expression Laboratory, Ludwig Institute for Cancer Research, Uppsala, Sweden.

1998 - 2003

Assistant Research Professor

Department of Medicine, University of California, Los Angeles, USA.

1997 - 1998

Assistant Research Cardiologist

Department of Medicine, University of California, Los Angeles, USA.

1995 - 1997

Postdoctoral Fellow

Departments of Biological Chemistry and Medicine, University of California, Los Angeles, USA.

1993 - 1995

  • The phosphorylation-dependent regulation of nuclear SREBP1 during mitosis links lipid metabolism and cell growth. Cell Cycle. 15: 2753-2765.
  • Fbw7 dimerization determines the specificity and robustness of substrate degradation. Genes Dev. 27: 2531-2536.
  • The ubiquitin ligase Fbxw7 controls adipocyte differentiation by targeting C/EBPalpha for degradation. Proc. Natl. Acad. Sci. U.S.A. 107, 11817-22.
  • The tumor suppressor Fbxw7 regulates TGFβ signaling by targeting TGIF1 for degradation. Oncogene 29, 5322-8.
  • A phosphorylation cascade controls the degradation of active SREBP1. (2009) J. Biol. Chem. 284, 5885-5895.
  • Hyperphosphorylation regulates the activity of SREBP1 during mitosis. Proc. Natl. Acad. Sci. U.S.A. 102, 11681–11686.
  • Control of lipid metabolism by phosphorylation-dependent degradation of the SREBP family of transcription factors by SCFFbw7. Cell Metabolism 1, 379-391.

  • 2009 - 2014 SFI Stokes Professor (salary support).
  • 2002 - 2007 Research Fellow of the Royal Swedish Academy of Sciences (salary support).
  • 2004 - Fernström Award for Young Scientists
  • 1994 & 1995 - Named "The George and Edna Lievre Family Research Fellow" by the American Heart Association.
  • 1995 - Named "The Wilfried Mommaerts Research Fellow" by the American Heart Association.
  • 1994 - 1996 Postdoctoral Research Fellowship from the American Heart Association.